Differences in functional connectivity (PLV and MI) between MCI and controls within frequency bands. (A) Theta band PLV based on centroid areas. (B) Theta band MI based on centroids areas; (C) Alpha band PLV based on PCA areas; (D) Alpha band MI based on PCA areas; (E) Broadband MI based on PCA areas; (F) Broadband MI based on areas centroids. Red lines: MCI > Controls; Blue Lines: Controls > MCI. (G) Receiving operator curve (ROC) of the support vector machine classifier trained using six FC-related variables. (H) Confusion matrix showing the positive predictive values and false discovery rate of the classifier. Abbreviations: MCI, mild cognitive impairment; PCA, principal component analysis; FC, functional connectivity; MI, mutual information; PLV, phase-locking value.