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. 2019 May 9;20(1):33–40. doi: 10.3892/mmr.2019.10215

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Copyright: © Liu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — The effect of miR-338-3p on the transcriptome of A549 cells. (A and B) Microarray assay showing that 216 genes were upregulated and 147 genes were downregulated in miR-338-3p-treated cells. (C) KEGG analysis showing the differentially expressed genes that were enriched for several signaling pathways, including the Jak-signal transducer and activator of transcription, PI3K/AKT and Wnt signaling pathways. cGMP-PKG, cyclic guanosine monophosphate-protein kinase G; Con, control; MAPK, mitogen-activated protein kinase; miR, microRNA; PI3k, phosphoinositide 3-kinase; TNF, tumor necrosis factor.