Table 2.
Multivariate analysis of predictors of moderate-to-high clinical severity*
| Predictors | OR | 95% CI | P |
|---|---|---|---|
| TMAO (per unit increase) | 1.22 | 1.08–1.32 | <0.001 |
| Age (per unit increase) | 1.25 | 1.03–1.42 | 0.013 |
| Infarct volume (per unit increase) | 1.15 | 1.03–1.30 | 0.009 |
| Atrial fibrillation (Yes vs. No) | 1.56 | 1.02–2.43 | 0.043 |
| Stroke etiology (CE vs. other) | 1.68 | 0.89–2.95 | 0.13 |
| FBG (per unit increase) | 1.68 | 0.95–3.16 | 0.092 |
| CRP (per unit increase) | 2.05 | 1.39–3.44 | 0.021 |
| HCY (per unit increase) | 1.09 | 1.02–1.22 | 0.034 |
*
Multivariable model included all of the following variables: age, sex, BMI, stroke syndrome, stroke etiology, vascular risk factors, pre-stroke treatment, lesion volumes and blood levels of TG, TC, HCY, Hs-CRP and FBG; moderate-to-high clinical severity is defined as NIHSS score > 5.