Table 4.

Multivariate analysis of CRYAB and p53 co-expression in DFS and OS in patients with ovarian cancer

Variable	Disease-free survival			Overall survival
	HR	95% CI	P-value	HR	95% CI	P-value
Expression of CRYAB and p53 (Double-positive vs Others)	3.46	1.830–6.528	0.000*	3.12	1.634–5.965	0.001*
Histological type (Serous vs Mucinous vs Endometroid vs Clear cell)	1.17	0.832–1.642	0.370	1.25	0.916–1.714	0.157
Lymph node metastasis (Positive vs Negative)	1.64	0.811–3.315	0.168	1.24	0.591–2.604	0.570
Distant metastasis (Positive vs Negative)	8.98	1.064–75.762	0.044	7.25	0.862–60.975	0.068
TNM stage (Stage I vs Stage II vs Stage III vs Stage IV)	0.06	0.009–0.473	0.007*	0.07	0.009–0.477	0.007*

Abbreviations: 95% CI, 95% confidence interval; HR, heart rate.

^*P<0.05.