Table III.
Hub genes identified in the protein interaction network.
| Name | Degree | Betweenness | Closeness |
|---|---|---|---|
| MAPK1 | 46 | 0.23654846 | 0.39900249 |
| PTEN | 36 | 0.22614707 | 0.39653036 |
| CREB1 | 35 | 0.18022213 | 0.3874092 |
| STAT3 | 25 | 0.05874048 | 0.3567447 |
| IFNG | 21 | 0.07357852 | 0.33264033 |
| FLT1 | 20 | 0.06162387 | 0.35087719 |
| RELA | 19 | 0.03995804 | 0.34042553 |
| IRS1 | 17 | 0.02215209 | 0.34820457 |
| DNAJC10 | 17 | 0.06587252 | 0.29767442 |
| CSNK2A1 | 16 | 0.07117248 | 0.34408602 |
| NCOR1 | 16 | 0.05439941 | 0.31496063 |
| NCK1 | 16 | 0.04186164 | 0.31714569 |
| SRF | 15 | 0.01578066 | 0.33229491 |
| REL | 13 | 0.01440785 | 0.34042553 |
| PAK3 | 13 | 0.02088241 | 0.31037827 |
| VHL | 13 | 0.02583072 | 0.30798845 |
| GNAI2 | 13 | 0.0176689 | 0.30563515 |
| SDHC | 13 | 0.03731446 | 0.33970276 |
| SNRPA | 12 | 0.07384247 | 0.33826638 |
| SOS1 | 12 | 0.02049813 | 0.33862434 |
| RAB7A | 12 | 0.07246042 | 0.30828516 |
| RBBP5 | 11 | 0.01080627 | 0.2640264 |
| EIF4E | 11 | 0.06378144 | 0.33229491 |
| NGFR | 11 | 0.02044841 | 0.32753327 |
| BCL6 | 11 | 0.0410574 | 0.34115139 |
| RPS14 | 10 | 0.04376657 | 0.27633851 |
| EPHA4 | 10 | 0.01262707 | 0.30710173 |
| PXN | 10 | 0.01479177 | 0.32520325 |
| EFTUD2 | 10 | 0.02160464 | 0.28725314 |
| UBE2L6 | 10 | 0.00749018 | 0.26380874 |
| NFATC2 | 10 | 0.00103466 | 0.31840796 |
| RHOQ | 10 | 0.02818871 | 0.28193833 |