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Expression of miR-144, Sfrp1 and TNF-α in clinical samples. (A) Expression of miR-144 was detected by reverse transcription-quantitative polymerase chain reaction analysis. Serum levels of (B) Sfrp1 and (C) TNF-α were detected by ELISA. (D) Correlation analysis was performed to examine the relationship between miR-144 and Sfrp1. Data represent the mean ± SEM. **P<0.01 and ***P<0.001. OP, osteoporosis; miR, microRNA; Sfrp1, secreted frizzled-related protein 1.
