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mTOR signaling and partial EMT in an AZD2014-treated large solid tumor of a Tsc2+/− mouse
A kidney section prepared from 16-month-old Tsc2+/− mice treated with vehicle or AZD2014 was used to examine mTOR signaling and EMT by IHC. Representative IHC-stained images were presented to show phosphorylation of S6 and Akt, and protein levels of vimentin, FSP1, and C-cadherin in solid tumors. Black lines are scale bars.
