Table I.
Gene numbers of the 48 sets of DEGs in hippocampus or striatum samples individually treated with ketamine, phencyclidine or memantine compared with the saline or normal group at 1, 2, 4 and 8 h, respectively.
| Hippocampus | Striatum | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Drug | Control | 1 h | 2 h | 4 h | 8 h | 1 h | 2 h | 4 h | 8 h |
| Ketamine | Saline | 13 (2,11) | 7 (6,1) | 2 (2,0) | 0 (0,0) | 113 (23,90) | 122 (30,92) | 235 (121,114) | 103 (41,62) |
| Normal | 7 (6,1) | 12 (5,7) | 8 (8,0) | 2 (1,1) | 50 (36,14) | 91 (47,44) | 64 (47,17) | 26 (23,3) | |
| Phencyclidine | Saline | 10 (3,7) | 4 (4,0) | 4 (1,3) | 0 (0,0) | 87 (46,41) | 106 (18,88) | 243 (119,124) | 98 (44,53) |
| Normal | 8 (4,4) | 14 (3,11) | 15 (10,5) | 5 (2,3) | 50 (41,9) | 43 (9,34) | 38 (21,17) | 31 (27,4) | |
| Memantine | Saline | 4 (4,0) | 18 (16,2) | 11 (6,5) | 1 (0,1) | 104 (13,91) | 99 (31,68) | 520 (241,279) | 89 (44,45) |
| Normal | 7 (7,0) | 16 (16,0) | 7 (7,0) | 1 (1,0) | 19 (14,5) | 43 (30,13) | 134 (60,74) | 13 (11,2) | |
Data are presented as the total number of DEGs (upregulated DEGs, downregulated DEGs). DEGs, differentially expressed genes.