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Knockdown of IGF1R inhibits activation of the AKT and STAT3 pathways. Expression levels and semi-quantitative analysis of AKT, STAT3, p-AKT, and p-STAT3 in IMR-32 (A and C) and SH-SY5Y (B and D) cells detected by Western blot. *P<0.05, **P<0.01 vs shNC group. All data are shown as the mean±SD based on three independent experiments.
Abbreviation: IGF1R, insulin-like growth factor 1 receptor.
