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. 2019 Jun 11;10:605. doi: 10.3389/fphar.2019.00605

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Copyright © 2019 Buchwald

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Fit of complex concentration-response data with the present model, Case VI: Activity data for fractional receptor-G protein coupling obtained with different opioids that share a peptidomimetic scaffold in δ- and μ-opioid receptors (top and bottom, respectively; after Vezzi et al., 2013) and fitted with the present model (Equation 19).