Table 3.
Baseline level: nonresponders versus responders
| Characteristics | Nonresponders | Responders | P Value |
|---|---|---|---|
| n, men, women | (10, 2, 8) | (14, 9, 5) | 0.03* |
| Age, yr | 65 ± 1 | 66 ± 1 | 0.47 |
| Body weight, kg | 96.97 ± 6.49 | 99.55 ± 2.72 | 0.69 |
| BMI, kg/m2 | 35.16 ± 1.61 | 35.34 ± 1.03 | 0.92 |
| Fat mass, kg | 44.78 ± 2.48 | 43.93 ± 2.26 | 0.80 |
| Fat mass, % | 46.59 ± 1.35 | 44.20 ± 2.05 | 0.38 |
| Fat-free mass, kg | 52.19 ± 4.56 | 55.62 ± 2.66 | 0.50 |
| Fat-free mass, % | 53.41 ± 1.35 | 55.80 ± 2.05 | 0.38 |
| Plasma GDF15, pg/ml | 654.07 ± 56.37 | 636.99 ± 62.54 | 0.85 |
| RER | 0.84 ± 0.01 | 0.88 ± 0.01 | 0.04 |
| FOX, mg·kg FFM−1·min−1 | 0.44 ± 0.06 | 0.25 ± 0.05 | 0.01 |
| Metabolic flexibility | 0.03 ± 0.01 | 0.01 ± 0.01 | 0.01 |
| HbA1C | 6.03 ± 0.23 | 5.39 ± 0.15 | 0.03 |
| V̇o2max, ml·kg FFM−1·min−1 | 35.36 ± 1.53 | 40.09 ± 1.02 | 0.02 |
Values are means ± SE; n = no. of subjects. BMI, body mass index; FFM, fat-free mass; GDF15, GDF15, growth differentiation factor 15; FOX, whole body fat oxidation; RER, respiratory exchange ratio; V̇o2max, maximal oxygen consumption.
*
Sex difference.