Table 3.
Functional enrichment analysis representing top 10 GO terms and pathways of DEGs in the SCLC group. Enriched terms were ranked based on the BH-adjusted p-value.
| GO ID | GO term | No. of Genes | BH-p-value |
|---|---|---|---|
| Biological Process | |||
| GO:0006260 | DNA replication | 38 | 2.82E-11 |
| GO:0051301 | Cell division | 59 | 1.96E-11 |
| GO:0006270 | DNA replication initiation | 17 | 1.33E-09 |
| Molecular Functions | |||
| GO:0005515 | Protein binding | 559 | 3.30E-09 |
| GO:0046982 | Protein heterodimerization activity | 60 | 1.12E-07 |
| GO:0042393 | Histone binding | 22 | 4.28E-04 |
| Cellular Components | |||
| GO:0005615 | Extracellular space | 144 | 7.73E-15 |
| GO:0070062 | Extracellular exosome | 242 | 5.36E-15 |
| GO:0000786 |
Nucleosome |
30 |
2.94E-13 |
| KEGG ID |
KEGG pathway |
No. of Genes |
BH-p-value |
| hsa05322 | Systemic lupus erythematosus | 37 | 1.17E-11 |
| hsa03030 | DNA replication | 18 | 1.33E-09 |
| hsa04110 | Cell cycle | 29 | 2.23E-07 |
| hsa04640 | Hematopoietic cell lineage | 20 | 4.25E-05 |
| hsa04512 | ECM-receptor interaction | 16 | 0.0113025 |