Table 1.
Urinary miRNAs dysregulated in kidney disease
| Disease | miRNA | Expression | Reference |
|---|---|---|---|
| Ischemia-reperfusion injury | |||
| Cardiac surgery | miRNA-21 | Up | 6, 15 |
| Kidney transplantation | miRNA-24 | Up | 42 |
| Intensive care unit | miRNA-494 | Up | 38 |
| Diabetic nephropathy | miRNA-15 | Down | 76 |
| Hypertension | |||
| Salt sensitivity | hsa-miRNA-4516 | Up | 21 |
| Renovascular hypertension | miRNA-26A | Down | 95 |
| Renovascular hypertension | miRNA-21,- miRNA-93, and miRNA-200b | Up | 36 |
| Polycystic kidney disease | miRNA-1 and miRNA-133b | Down | 8 |
| Glomerulonephritis | |||
| IgA nephropathy | miRNA-146a and miRNA-155 | Up | 41, 83 |
| Focal segmental glomerulosclerosis | miRNA-10a and miRNA-30d | Up | 84 |
| Lupus nephritis | miRNA-146a | Up | 61, 93 |
| Kidney transplantation | |||
| Acute T cell-mediated rejection | miRNA-210 | Down | 44 |
| Chronic rejection | miRNA-142-3p, miRNA-204, and miRNA-211 | Up and down | 67, 73 |
| Ureteral obstruction | let-7a and miRNA-29b | Down | 57 |
| Cancer | |||
| Bladder cancer | miRNA-126 and miRNA-152 | Up and down | 4, 16, 27 |
| Renal cell carcinoma | miRNA-15 | Up | 55, 81 |
miRNA, microRNA.