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. 2019 Mar 20;316(5):F1016–F1025. doi: 10.1152/ajprenal.00607.2018

Fig. 6.

Fig. 6.

Representative renal cross sections (one per animal from a n = 7 per group) stained with trichrome, morphometric analysis, and representative bands showing renal protein expression (two per animal from a n = 7 per group) and quantification of matrix-metallopeptidase-2 and -9 (MMP-2 and MMP-9), tissue transglutaminase (tTg), tissue metallopeptidase inhibitor-1 (TIMP-1), thrombospondin (THBS), and osteopontin (OPN) from normal, renal angioplasty and stenting (PTRAs) and PTRAs+ elastin-like polypeptide-vascular endothelial growth factor (ELP-VEGF)-treated kidneys.A: coadjuvant intrarenal ELP-VEGF administration during PTRAs attenuated renal fibrosis and glomerulosclerosis. B: changes in renal morphology were accompanied by a shift in protein expression of factors involved in extracellular matrix turnover. †P < 0.05 versus RVD+PTRAs. *P < 0.05 versus Normal. #P = 0.06 versus RVD+PTRAs. ^P = 0.07 versus RVD+PTRAs.