Similar intake and urinary production in wild-type (WT) and transient receptor potential vanilloid type 4 (TRPV4)−/− mice during acute K+ deficiency. A and B: summary graphs showing a comparison of 24-h food (A) and water (B) intake in male WT, male TRPV4−/−, and female TRPV4−/− mice maintained on a regular K+ diet (0.9% K+) and in response to a K+-deficient diet (<0.01% K+) for 1 or 2 days. C: summary graph showing the comparison of whole body animal weights of male WT, male TRPV4−/−, and female TRPV4−/− mice used for balance experiments. D: summary graph showing a comparison of 24-h urinary output in male WT, male TRPV4−/−, and female TRPV4−/− mice maintained on a regular K+ diet (0.9% K+) and in response to a K+-deficient diet (<0.01% K+) for 1 or 2 days. Values are means ± SE; n, number of experimental animals for each group. *Significant increase versus the respective values on the regular K+ diet.