Fig. 2.

Effects of GlcNH₂ and MelNH₂ on IL-2 production and cell number (viability) in Jurkat cells. Cells were pre-incubated for 30 min in the absence or presence of the indicated concentrations of GlcNH₂ or MelNH₂ (A–D), or 1 μM CsA (A, B). After the addition of ConA (A, C, D) or the combination of PMA (1 μM) and IM (0.5 μM) (B), cells were further incubated for 12 h and assayed for IL-2 protein production (A, B), living cell number (C), and cell viability (D). *P < 0.05, **P < 0.01, ***P < 0.001; unpaired t-test (2-tailed), as compared with control.