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. 2019 Jun 14;25(22):2776–2787. doi: 10.3748/wjg.v25.i22.2776

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©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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STC2 was hypermethylated in colon cancer tissues and the high expression of STC2 indicated poor prognosis. A: Comparison of the promoter methylation level of STC2 in 37 cases normal colon and 313 cases tumor tissues; B: The cumulative survival rate was conducted between high and low expression of STC2. ^cP < 0.001 vs normal. STC2: Stanniocalcin 2.