Table 3.
Outcome | Immunomodulators | Systemic steroid | Biologic agents | |||
Yes (n = 10199) | No (n = 27497) | Yes (n = 21606) | No (n = 16090) | Yes (n = 2075) | No (n = 35621) | |
Atrial fibrillation | 85 | 263 | 227 | 121 | 21 | 327 |
Incidence rate1 | 1.72 | 1.97 | 2.21 | 1.50 | 2.16 | 1.89 |
Adjusted HR2 (95%CI) | 1.46 (1.13-1.89) | 1 (reference) | 1.37 (1.10-1.71) | 1 (reference) | 2.38 (1.51-3.75) | 1 (reference) |
Incidence rates were calculated per 1000 patient-years, within the population who were over 20 years old and not previously diagnosed with atrial fibrillation;
Adjusted with age, sex, place, income, diabetes mellitus, hypertension, dyslipidemia, previous history of stroke, ischemic heart disease, and end stage renal disease. HR: Hazard ratio; CI: Confidence interval.