Table 4.

Clinical Associations of myositis associated autoantibodies.

	Positive Clinical Associations				Negative Clinical Associations
	Clinical Association	p value	OR	95% CI	Clinical Association	p value	OR	95% CI
Anti-PMScl n = 119	Mechanic's hands	<0.001	16.34	9.29–28.76	V-Sign Rash	= 0.049	0.46	0.21–1.00
	CTD-Overlap	<0.001	6.74	4.44–10.22
	Raynaud's	<0.001	6.44	3.78–10.98
	ILD	<0.001	6.28	4.12–9.57
	Dysphagia	<0.001	3.70	2.24–6.11
	Rash (any DM)1	<0.001	2.68	1.82–3.95
	Periungual Erythema	= 0.002	2.49	1.39–4.45
	Gottron's Rash	<0.001	2.23	1.47–3.40
Anti-Ku n = 13	CTD-Overlap	<0.001	9.97	2.63–24.16
	Arthritis	= 0.009	7.71	1.66–35.90
	Raynaud's	= 0.013	7.39	1.52–35.92
	ILD	= 0.007	4.90	1.53–15.72
Anti-Ro60 n = 19	CTD-Overlap	<0.001	5.42	2.09–14.08
Anti-U1RNP/Sm n = 65	CTD-Overlap	<0.001	18.17	10.46–31.57	Gottron's Rash	= 0.014	0.31	0.12–0.79
	Raynaud's	<0.001	15.21	5.88–39.35	Heliotrope Rash	= 0.046	0.44	0.19–0.98
	Dysphagia	<0.001	3.37	1.66–6.80
	ILD	<0.001	2.96	1.67–5.27

Results are shown on an analysis of 1483 patients with either a single MSA or MAA or no identifiable autoantibody on immunoprecipitation. ¹Rash (any DM): presence of any one of heliotrope, Gottron's, shawl sign or V sign dermatomyositis rash. ILD: Interstitial Lung Disease, CTD: Connective Tissue Disease, OR: Odds Ratio, CI: Confidence Interval.