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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: J Allergy Clin Immunol. 2019 Jan 14;143(4):1465–1473. doi: 10.1016/j.jaci.2018.12.1003

TABLE I.

Reported cases of anaphylaxis: General characteristics by age group, 1990–2016

<4 y (%),
n = 118
4–10 y (%),
n = 267
11–18 y (%),
n = 93
19–49 y (%),
n = 233
≥50 y (%),
n = 117
Total (%),
n = 828
Seriousness of report
 Deaths 1 (1) 0 (0) 0 (0) 3 (1) 4 (3) 8 (1)
 Serious, nondeath* 98 (83) 229 (86) 70 (75) 173 (74) 84 (72) 654 (79)
 Nonserious 19 (16) 38 (14) 23 (25) 57 (24) 29 (25) 166 (20)
Sex of reported patient
 Male 77 (65) 189 (71) 43 (46) 40 (17) 31 (26) 380 (46)
 Female 40 (34) 78 (29) 50 (54) 193 (83) 86 (74) 447 (54)
 Not reported 1 (1) 0 (0) 0 (0) 0 (0) 0 (0) 1 (0)
Time to onset of symptoms
 <30 min 59 (50) 176 (66) 36 (39) 96 (41) 35 (30) 402 (49)
 30–119 min 27 (23) 46 (17) 18 (19) 58 (25) 18 (15) 167 (20)
 2–4 h 11 (9) 7 (3) 16 (17) 27 (12) 18 (15) 79 (10)
 4–8 h 8 (7) 6 (2) 2 (2) 13 (6) 15 (13) 44 (5)
 8–24 h 7 (6) 2 (1) 7 (8) 12(5) 15 (13) 43 (5)
 Not reported 6(5) 30 (11) 14 (15) 27 (12) 16 (14) 93 (11)
Classification
 Brighton level 1 64 (54) 157 (59) 44 (47) 81 (35) 39 (33) 385 (46)
 Brighton level 2 42 (36) 81 (30) 24 (26) 114 (49) 54 (46) 315 (38)
 Brighton level 3 2 (2) 1 (0) 1 (1) 2 (1) 1 (1) 7 (1)
 Physician diagnosed 10 (8) 28 (10) 24 (26) 36 (15) 23 (20) 121 (15)
*

Reports in which the patient was hospitalized, had prolongation of hospitalization, had permanent disability, or experienced a life-threatening condition.