Table 1.
Baseline characteristics between CN and DQ groups
| Mean ± SD (Range) | |||
|---|---|---|---|
| CN (n = 58) | DQ (n = 57) | p-value | |
| Age (years) | 47.21 ± 15.91 (24 ~ 81) | 43.86 ± 16.74(22 ~ 79) | 0.2594 |
| Gender (M/F)a | 6/52 | 7/50 | 0.7431 |
| Corneoconjunctival staining (NEI scale) | 10.78 ± 5.02 (4.00 ~ 27.00) | 10.25 ± 4.89 (4.00 ~ 23.00) | 0.5220 |
| Corneal staining | 5.47 ± 1.70 (4.00~10.00) | 5.68 ± 1.84 (4.00 ~ 10.00) | 0.5968 |
| Conjunctival staining | 5.31 ± 4.18 (0.00 ~ 18.00) | 4.56 ± 3.71(0.00 ~ 15.00) | 0.3089 |
| TBUT (sec) | 3.87 ± 1.32 (1.05 ~ 8.67) | 4.29 ± 1.85 (0.50 ~ 8.42) | 0.3459 |
| Schirmer test (mm) | 8.67 ± 6.30 (2.00 ~ 35.00) | 7.96 ± 5.55 (1.00 ~ 30.00) | 0.3955 |
| OSDI (0–100) | 43.36 ± 20.61 (8.00 ~ 94.00) | 42.46 ± 18.90 (2.00 ~ 98.00) | 0.8065 |
Comparison between CN and DQ groups by Wilcoxon rank sum test
CN 0.05% cyclosporin nanoemusion (0.5 mg/mL), DQ 3% diquafosol sodium (30 mg/mL), SD standard deviation, TBUT tear break up time, OSDI ocular surface disease index
aχ2 test