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. 2019 Jun 17;19:599. doi: 10.1186/s12885-019-5808-9

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — SZ168 suppresses pulmonary metastasis in vivo. CHO/hPDPN cells were incubated with 30 μg SZ168 or mouse IgG. Cell suspensions were intravenously inoculated into BALB/c nude mice. (a) Comparison of the tumor sizes and tumor incidences in mice on day 30. (b) Representative pictures of the lungs. (c) Gross morphology of the tumors. (d) Lung weights. *P < 0.05. (e) Numbers of metastatic foci of the lungs. ***P < 0.001. (f) Tumor events. ***P < 0.001. Arrows indicate subcutaneous tumors. Data are presented as mean ± SD from three independent experiments (n = 6)