Table 3.
Adjusteda hazards ratios and 95% confidence intervals for the predictors of cardiovascular disease
| Predictor variable | Men (n = 485) | Women (n = 492) | ||
|---|---|---|---|---|
| HR (95% CI) | P-value | HR (95% CI) | P-value | |
| Sociodemographic variables | ||||
| Age per 10 years | 1.50 (1.19–1.89) | 0.001 | 1.10 (0.77–1.56) | 0.597 |
| History of smoking | 1.80 (1.07–3.02) | 0.027 | 0.00 (0.00–3.07) | 0.967 |
| Treatment modalities | ||||
| Antidiabetic drugs | 0.87 (0.41–1.82) | 0.706 | 1.67 (0.67–4.15) | 0.274 |
| Antihypertensive agents | 0.84 (0.42–1.68) | 0.621 | 0.73 (0.28–1.93) | 0.530 |
| Lipid-lowering medication | 0.81 (0.44–1.49) | 0.497 | 1.04 (0.42–2.58) | 0.935 |
| Anthropometric parameters | ||||
| BMI (kg/m2) | 1.00 (0.96–1.05) | 0.982 | 0.96 (0.92–1.02) | 0.175 |
| SBP per 10 mmHg | 1.20 (1.01–1.44) | 0.042 | 1.58 (1.27–1.96) | < 0.001 |
| DBP per 10 mmHg | 1.00 (0.77–1.31) | 0.998 | 0.71 (0.50–1.01) | 0.056 |
| Laboratory parameters | ||||
| TC/HDL-C ratio | 0.95 (0.77–1.17) | 0.613 | 1.44 (1.02–2.04) | 0.037 |
| LDL-C (mmol/L) | 1.10 (0.83–1.44) | 0.516 | 0.80 (0.50–1.30) | 0.365 |
| eGFR (mL/min.1.73 m2) | 0.98 (0.97–0.99) | < 0.001 | 0.98 (0.97–1.00) | 0.043 |
| HbA1c (%) | 1.16 (1.02–1.32) | 0.029 | 1.24 (1.03–1.49) | 0.022 |
BMI body mass index, eGFR estimated glomerular filtration rate, SBP systolic blood pressure, DBP diastolic blood pressure, TC total cholesterol, HDL-C high-density lipoprotein-cholesterol, LDL-C low-density lipoprotein-cholesterol, HbA1c glycosylated hemoglobin A1c, HR hazards ratio, CI confidence interval
aMultivariable Cox model adjusted for all of the predictors in the final model