Skip to main content
. 2019 May 23;10(6):978–984. doi: 10.1021/acsmedchemlett.9b00170

Table 6. Effect of Compounds 4, 2425, and 2730 on HepG2.

    HepG2 GI50 (μM)
compd SMYD3 IC50 (μM) 2D 3D
4 4.78 ± 0.026 >100 n.d.
24 0.3 ± 0.017 >100 n.d.
25 0.17 ± 0.014 24.36 0.79
27 0.26 ± 0.026 >100 n.d.
28 0.25 ± 0.015 >100 n.d.
29 0.0117 ± 0.0109 17.69 1.04
30 >250 60.77 >10