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. 2019 Jun 17;20:223. doi: 10.1186/s12882-019-1394-y

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Effect of advanced administration of anisodamine/atropine on kidneys in rats subjected to glycerol-induced AKI. a Serum Scr in groups of male SD rats (n = 6) given intramuscular injections of 50% glycerol (10 mL/kg) with anisodamine (1 mg/kg) and atropine (0.05 mg/kg) by intraperitoneal injection 20 min before glycerol treatment. The control group did not receive any treatment. Data are expressed as the mean ± SEM (n = 6). #, statistically significantly different from respective 0 h controls; *, statistically significantly different from rats receiving glycerol treatment alone at the corresponding time point (P < 0.05). b Serum BUN in groups of male SD rats (n = 6) given intramuscular injections of 50% glycerol (10 mL/kg), with anisodamine (1 mg/kg) and atropine (0.05 mg/kg) by intraperitoneal injection 20 min before glycerol treatment. The control group did not receive any treatment. Data are expressed as the mean ± SEM (n = 6). #, statistically significantly different from respective 0 h controls; *, statistically significantly different from rats receiving glycerol treatment alone at the corresponding time point (P < 0.05). c Serum CK in groups of male SD rats (n = 6) injected intramuscularly with 50% glycerol (10 mL/kg), with anisodamine (1 mg/kg) and atropine (0.05 mg/kg) by intraperitoneal injection 20 min before glycerol treatment. The control group did not receive any treatment. Data are expressed as the mean ± S.E. (n = 6). #, statistically significantly different from respective 0 h controls (P < 0.05). *, statistically significantly different from rats receiving glycerol treatment alone at the corresponding time point (P < 0.05)