Table 4.
Association between energy and protein intakes and 28-day mortality as well as nutritional status stratified by days on exclusive nutritional support and GLIMPSE groups
| Parameters | Short-term ENS (≤ 6 days) | Longer-term ENS (≥ 7 days) | p value | |||
|---|---|---|---|---|---|---|
| Low-GLIMPSE* (n = 36) | High-GLIMPSE* (n = 70) | Low-GLIMPSE* (n = 64) | High-GLIMPSE* (n = 82) | |||
| Energy intake | 0.793† | 0.035‡ | ||||
| Each 10% of goal | 1.24 (0.70–2.20) | 1.60 (1.19–2.15) | 2.17 (0.75–6.26) | 0.83 (0.64–1.12) | ||
| p = 0.462 | p = 0.002 | p = 0.150 | p = 0.228 | |||
| GOF = 0.682 | GOF = 0.823 | GOF = 0.287 | GOF = 0.615 | |||
| Protein intake | 0.904§ | 0.025** | ||||
| Each 10% of goal | 1.20 (0.68–2.11) | 1.47 (1.12–1.86) | 1.23 (0.73–2.08) | 0.75 (0.57–0.99) | ||
| p = 0.535 | p = 0.004 | p = 0.428 | p = 0.043 | |||
| GOF = 0.685 | GOF = 0.530 | GOF = 0.455 | GOF = 0.335 | |||
| 7-point SGA-categories | 0.480†† | 0.633‡‡ | ||||
| Well-nourished | ||||||
| SGA-7 | 22 [61.1] | 34 [48.6] | 41 [64.1] | 34 [41.5] | ||
| SGA-6 | 8 [22.2] | 11 [15.7] | 18 [28.1] | 18 [22.0] | ||
| Mildly to moderately malnourished | ||||||
| SGA-5 | 3 [8.3] | 8 [11.4] | 4 [6.3] | 14 [17.1] | ||
| SGA-4 | 2 [5.6] | 7 [10.0] | 1 [1.6] | 9 [11.0] | ||
| SGA-3 | 1 [2.8] | 5 [7.1] | 0 [0.0] | 5 [6.1] | ||
| Severely malnourished | ||||||
| SGA-2 | 4 [5.7] | 2 [2.4] | ||||
| SGA-1 | 1 [1.4] | 0 [0.0] | ||||
Values are adjusted odds ratio (95% confidence interval) adjusted for days on exclusive nutritional support and count [percentage]. Refer to Additional file 1 for beta weights of potential confounders not included in the model
ENS exclusive nutritional support, GLIMPSE Global Index of Mortality Probability in the Severely ill, GOF goodness of fit derived from Hosmer-Lemeshow test, SGA Subjective Global Assessment
*Low- and high-GLIMPSE is defined as the predicted mortality risk of < 20% and > 20%, respectively
†Interaction between energy intake and GLIMPSE categories in patients with short-term exclusive nutritional support
‡Interaction between energy intake and GLIMPSE categories in patients with longer-term exclusive nutritional support
§Interaction between protein intake and GLIMPSE categories in patients with shorter-term exclusive nutritional support
**Interaction between protein intake and GLIMPSE categories in patients with longer-term exclusive nutritional support
††Comparison of 7-point SGA categories between low-GLIMPSE patients with short-term and longer-term ENS
‡‡Comparison of 7-point SGA categories between high-GLIMPSE patients with short-term and longer-term ENS