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. 2019 Jun 17;19:595. doi: 10.1186/s12885-019-5820-0

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Frequency of EGFRex20ins mutations. a. Comparison of EGFRex20ins frequency in total NSCLC patients (OrigiMed 2.3% vs. FM 1.8%, p = 0.12) and adenocarcinoma patients (OrigiMed 2.7% vs. FM 2.3%, p = 0.32). b. Comparison of EGFRex20ins frequency in EGFR-mutant NSCLC patients (OrigiMed 4.8% vs. FM 11.7%, p < 0.001) and EGFR-mutant adenocarcinoma patients (OrigiMed 4.8% vs. FM 13.9%, p < 0.001). EGFRex20ins, epidermal growth factor receptor exon 20 insertions; NSCLC, non-small cell lung cancer; FM: Foundation Medicine. * p < 0.001