TABLE 1.

Overall frequencies of paw or digit swelling in mice of the TTP^{ΔCNBD/ΔCNBD} and TTP^ΔCNBD/− genotypes

Parameter	% of mice with indicated genotype on indicated genetic background
	TTPΔCNBD/ΔCNBD				TTPΔCNBD/−
	B6		129		B6		129
	Male	Female	Male	Female	Male	Female	Male	Female
Swellinga	50	73	71	82	93	65	95	100
Resolvedb	29	55	30	22	54	36	0	0
Improvedc	29	36	0	0	8	0	0	0

^aPercentage of mice that exhibited any swelling of digits or paws that occurred at any time during the 24-week observation period, even if transient.

^bRepresents a subgroup of the “Swelling” group and refers to mice with complete resolution of swelling by the end of the observation period, i.e., no swelling of any digits at the end of the experiment.

^cRefers to mice with partial resolution of swelling at the end of the observation period, either less swelling of affected digits or fewer affected digits.