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. 2019 Jan 11;73(3):193–197. doi: 10.1136/jech-2018-210920

Figure 1.

Figure 1

Suggestion of shifting paradigm from a chemical-focused to a human-focused approach in the low-dose range of chemical mixtures. Traditional approaches such as strict regulation or avoidance of exposure sources are effective to protect humans from harms of individual or several chemicals in the high-dose range. In the low-dose range, methods to control or fight against them in the human body should be investigated. Exercise and healthy diet (high dietary fibre, high phytochemicals, calorie restriction and intermittent fasting) can be considered for these purposes.