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. 2018 Nov 24;68(4):654–662. doi: 10.1136/gutjnl-2018-317178

Figure 2.

Figure 2

Taxonomic distribution of enteric fungi in colorectal cancer (CRC). (A) Relative abundance of dominant enteric fungi phyla in control, n=92 and CRC, n=73. The dominant phyla are Ascomycota, Basidiomycota and Mucoromycota in both groups. (B) Basidiomycota:Ascomycota relative abundance ratio, an index of fungal dysbiosis, is higher in CRC, n=73 than control, n=92 (**p<0.001, Mann-Whitney U test). (C) Differentially abundant fungal classes between CRC (n=73) and control (n=92). Differences in abundance were detected using multivariate statistical model and corrected for confounders including age, Body Mass Index (BMI) and gender (*Q<0.20, **Q<0.10, ***Q<0.05, arcsin-sqrt transformation of relative abundance are derivatives of MaAsLin). (D) Differentially abundant fungal families between CRC, n=73 and control, n=92. Differences in abundance were detected using multivariate statistical model and corrected for confounders including age, BMI and gender (*Q<0.20, **Q<0.10, ***Q<0.05, arcsin-sqrt transformation of relative abundance are derivatives of MaAsLin). (E) Differentially abundant fungal genera between CRC, n=73 and control, n=92. Differences in abundance were detected using multivariate statistical model and corrected for confounders including age, BMI and gender (*Q<0.20, **Q<0.10, ***Q<0.05, arcsin-sqrt transformation of relative abundance are derivatives of MaAsLin).