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. Author manuscript; available in PMC: 2019 Jun 18.
Published in final edited form as: J Clin Pathol. 2018 Nov 22;72(3):258–262. doi: 10.1136/jclinpath-2018-205570

Figure 1. MED12 and TERT mutational frequency and spectrum of MED12 exon 2 mutations in fibroepithelial lesions in young patients.

Figure 1.

Representative photomicrographs of (a) a fibroadenoma (FA) and (b) a benign phyllodes tumor (BePT) from this series. Scale bars, 100 μm (c) Frequency of MED12 exon 2 mutations in FAs (n=21) and BePTs (n=8) in adolescents and young adults, identified by Sanger sequencing. (d) MED12 protein domain structure and detailed view of exon 2, depicting the 13 and 7 mutations identified in the 21 FAs and 8 BePTs from this study, respectively. aa, aminoacid; BePTs, benign phyllodes tumors; SNV, single-nucleotide variant.