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. 2018 Dec 11;105(6):439–448. doi: 10.1136/heartjnl-2018-313463

Table 3.

Associations between occupational exposures and cardiovascular disease and subtypes (n=7404)

Crude model Adjusted model 1 Adjusted model 2 Adjusted model 3
PR (95% CI)* PR (95% CI)† PR (95% CI)‡ PR (95% CI)§
Cardiovascular disease
 Solvents 1.03 (0.64 to 1.66) 0.93 (0.58 to 1.51) 0.94 (0.58 to 1.52) 0.92 (0.58 to 1.47)
 Metals 1.21 (0.80 to 1.83) 1.26 (0.81 to 1.95) 1.24 (0.80 to 1.93) 1.22 (0.79 to 1.89)
 Pesticides 2.51 (1.35 to 4.69) 2.25 (1.26 to 4.01) 2.18 (1.34 to 3.55) 2.18 (1.34 to 3.56)
Coronary heart disease
 Solvents 1.12 (0.67 to 1.86) 0.97 (0.59 to 1.60) 0.96 (0.59 to 1.57) 0.96 (0.59 to 1.57)
 Metals 1.05 (0.65 to 1.69) 1.01 (0.61 to 1.67) 0.97 (0.59 to 1.59) 0.98 (0.60 to 1.59)
 Pesticides 2.85 (1.30 to 6.26) 2.47 (1.24 to 4.90) 2.20 (1.31 to 3.71) 2.24 (1.29 to 3.90)
Cerebrovascular disease
 Solvents 0.70 (0.25 to 1.97) 0.59 (0.20 to 1.70) 0.59 (0.20 to 1.76) 0.60 (0.22 to 1.64)
 Metals 0.59 (0.24 to 1.42) 0.65 (0.25 to 1.67) 0.67 (0.26 to 1.76) 0.64 (0.25 to 1.65)
 Pesticides 1.48 (0.67 to 3.24) 1.33 (0.58 to 3.04) 1.38 (0.62 to 3.03) 1.42 (0.64 to 3.14)
Atrial fibrillation
 Solvents 1.34 (0.20 to 8.97) 1.46 (0.21 to 10.23) 1.62 (0.32 to 8.31) 1.25 (0.28 to 5.47)
 Metals 2.45 (0.73 to 8.27) 2.88 (0.81 to 10.29) 3.78 (1.24 to 11.46) 3.93 (1.41 to 11.00)
 Pesticides 4.00 (1.10 to 14.51) 3.52 (0.80 to 15.46) 5.92 (1.89 to 18.61) 5.61 (1.97 to 16.03)
Heart failure
 Solvents 0.36 (0.10 to 1.30) 0.38 (0.10 to 1.41) 0.40 (0.11 to 1.48) 0.41 (0.11 to 1.51)
 Metals 0.91 (0.18 to 4.49) 1.27 (0.22 to 7.15) 1.53 (0.27 to 8.69) 1.56 (0.28 to 8.64)
 Pesticides 0.85 (0.22 to 3.30) 0.86 (0.23 to 3.27) 0.91 (0.23 to 3.54) 0.92 (0.23 to 3.70)

*Prevalence ratio (PR) with 95% CI comparing self-reported exposure to the respective agent to no exposure.

†PR with 95% CI comparing self-reported exposure to the respective agent to no exposure with adjustment for age (restricted cubic splines with four knots), gender (male/female), field centre (Bronx, Chicago, Miami or San Diego) and Hispanic/Latino background (Dominican, Central American, Cuban, Mexican, Puerto Rican, South American or other/mixed).

‡PR with 95% CI comparing self-reported exposure to the respective agent to no exposure with adjustment for the variables listed in † with additional adjustments for current health insurance status (yes/no), cigarette use (current, former or never), alcohol use level (none, low/moderate or high) years of residential duration in the USA (restricted cubic splines with four knots), employment status (full time or part time), physical activity level (low, medium or high), alternative healthy eating index (restricted cubic splines with four knots) and the Short Acculturation Scale for Hispanics – language subscale (restricted cubic splines with four knots).

§PR with 95% CI comparing self-reported exposure to the respective agent to no exposure with adjustment for the variables listed in † with additional adjustments for hypertension (yes/no), hypercholesterolaemia (yes/no), body mass index (restricted cubic splines with four knots) and diabetes mellitus (yes/no).