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. 2018 Oct 3;19(1):49–55. doi: 10.1136/practneurol-2018-001935

Table 2.

Sensitivity of CSF RT-QuIC in different sCJD subtypes

sCJD subtype Sensitivity (%)
First-generation RT-QuIC12 (total number cases investigated)		 Sensitivity (%)
Second-generation RT-QuIC16 (total number cases investigated)
MM1/MV1 89 (111) 96 (119)
MV2 81 (26) 89 (9)
MM2 42 (10) 78 (9)
VV1 100 (1) 75 (8)
VV2 78 (27) 100 (27)

CSF, cerebrospinal fluid; MM, methionine; MV, methionine and valine; RT-QuIC, real-time quaking-induced conversion; sCJD, sporadic Creutzfeldt-Jakob disease;VV, valine.