Table 5.
TCP, α/β=1.5 Gy | TCP, α/β=3 Gy | TCP, α/β=10 Gy | |||||
Prostate-DILa | DIL | Prostate-DIL | DIL | Prostate-DIL | DIL | ||
Patients with EBRT (8) | I b | 89.3 ± 4.8 | 61.7 ± 28.5 | 85.2 ± 6.2 | 50.4 ± 33.2 | 63.3 ± 11.7 | 25.3 ± 33.0 |
II | 87.8 ± 4.9 | 83.6 ± 13.9 | 83.4 ± 6.1 | 75.9 ± 19.8 | 60.5 ± 11.5 | 45.8 ± 33.9 | |
III | 87.4 ± 6.0 | 90.1 ± 7.5 | 83.1 ± 6.9 | 85.2 ± 11.3 | 60.7 ± 12.1 | 59.1 ± 27.1 | |
P-values | |||||||
I vs II | 0.250 | 0.008 | 0.195 | 0.016 | 0.250 | 0.008 | |
I vs III | 0.469 | 0.016 | 0.469 | 0.016 | 0.297 | 0.016 | |
II vs III | 0.297 | 0.031 | 0.219 | 0.031 | 0.219 | 0.031 | |
Patients without EBRT (9) | I | 94.8 ± 0.7 | 89.5 ± 16.9 | 91.1 ± 1.1 | 84.5 ± 21.0 | 70.8 ± 2.9 | 63.0 ± 25.3 |
II | 94.5 ± 1.1 | 96.1 ± 5.2 | 90.6 ± 1.6 | 93.5 ± 8.4 | 69.9 ± 4.1 | 80.3 ± 19.6 | |
III | 94.3 ± 1.4 | 97.3 ± 3.0 | 90.3 ± 2.2 | 95.3 ± 5.2 | 69.0 ± 5.5 | 84.8 ± 14.9 | |
P-values | |||||||
I vs II | 0.258 | 0.004 | 0.250 | 0.004 | 0.426 | 0.004 | |
I vs III | 0.219 | 0.004 | 0.301 | 0.004 | 0.359 | 0.004 | |
II vs III | 0.805 | 0.008 | 0.734 | 0.008 | 0.652 | 0.008 | |
NTCP | |||||||
Bladder | Rectum | Uretha | |||||
Patients with EBRT (8) | I | 10.5 ± 9.8 | 0 | 71.0 ± 2.1 | |||
II | 11.1 ± 7.3 | 0 | 72.1 ± 1.8 | ||||
III | 8.5 ± 4.2 | 0 | 71.8 ± 1.8 | ||||
P-values | |||||||
I vs II | 0.945 | N/A | 0.008 | ||||
I vs III | 0.938 | N/A | 0.016 | ||||
II vs III | 0.297 | N/A | 0.688 | ||||
Patients without EBRT (9) | I | 0.1 ± 0.2 | 0 | 46.1 ± 5.9 | |||
II | 0.5 ± 1.2 | 0 | 48.4 ± 6.3 | ||||
III | 0.2 ± 0.4 | 0 | 48.9 ± 6.9 | ||||
P-values | |||||||
I vs II | 0.652 | N/A | 0.004 | ||||
I vs III | 0.570 | N/A | 0.008 | ||||
II vs III | 0.426 | N/A | 0.250 |
Prostate - DIL = Prostate with DIL cropped.
I, II and III are “Original”, “Original Boost” and “Additional Boost” plans, respectively.