Table 2.
The diagnostic performance between malignant and benign prostate lesion for different parameters
| Parameters | AUC 95% CI） | Optimal cut-off value |
Sensitivity
(%) |
Specificity
(%) |
Youden index |
PPV
(%) |
NPV
(%) |
| Emax | 0.855 (0.804–0.905) | 128.48 kPa | 77.88 | 85.33 | 0.6121 | 83.02 | 77.06 |
| Emean | 0.842 (0.788–0.895) | 62.27 kPa | 81.42 | 74.51 | 0.5593 | 77.97 | 78.35 |
| Emin | 0.588 (0.512–0.665) | 20.03 kPa | 60.18 | 63.73 | 0.2390 | 64.15 | 58.72 |
| PSA | 0.910 (0.870–0.951) | 37.01 ng ml−1 | 74.34 | 98.04 | 0.7238 | 96.55 | 77.34 |
AUC, area under the receiver operating characteristic curves; CI, confidence interval; Emax, maximum Young’s modulus; Emean, mean Young’s modulus; Emin, minimum Young’s modulus; NPV, negative predictive value; PPV, positive predictive value; PSA, prostate specific antigen.