TABLE 1.

Mutations identified in the 3D polymerase regions of the SVA in passage 10

Clone	Mutation in 3D polymerase regions of viral population
	H79R	V94A	I212V	V218A	S460L
M1				X	X
M2		X
M3			X		X
M4					X
M5					X
M6					X
M7					X
M8	X				X
M9					X
M10					X