FIG 8.

Formation of a bud neck (white arrowheads). (A) Virtual section of a representative budding HCMV capsid based on three-dimensional STEM tomography showing a bud neck. Scale bar, 100 nm. (B and C) Three-dimensional visualizations of the capsid in panel A which show that the vesicle membrane (green, semitransparent) has a large tubular shape. Orange, capsid; blue, tegument. (C) Cross section through the vesicle as shown in image A. The cross section through the tegument is shown in light blue. (B and D) Views of the vesicle from different angles (see Movie S1 in the supplemental material).