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Interferon mRNA expression in hippocampus explants. The levels of IFN-α (A), IFN-β (B), and MX1 (C) mRNA were quantified over time in slices from SLAM transgenic mice (n = 7), and SLAM × IFNARKO transgenic mice (n = 5) at days 0, 3 and 7 of culture. All RNA quantifications were done by RT-qPCR and normalized to the variation of the amounts of GAPDH mRNA. Statistical analyses were performed using the Kruskal-Wallis test. *, P < 0.05; **, P < 0.01.
