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. 2019 Jun 11;10:1248. doi: 10.3389/fimmu.2019.01248

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Copyright © 2019 Madkaikar, Shabrish, Kulkarni, Aluri, Dalvi, Kelkar and Gupta.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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NK cell degranulation assay results. (A) Samples were analyzed by flow cytometry, gating on lymphocytes by forward/side scatter. (B) NK cells were gated based on (CD56+CD3-). CD107a expression was analyzed on unstimulated and Ca-I + PMA stimulated natural killer (NK) cells (CD56+CD3-). Degranulation assay results are shown from (C) healthy control (representative plot) and (D) FHL patients with degranulation defect.