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. 2019 Jun 11;10:1248. doi: 10.3389/fimmu.2019.01248

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Copyright © 2019 Madkaikar, Shabrish, Kulkarni, Aluri, Dalvi, Kelkar and Gupta.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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CGD analysis. (A) Samples were analyzed by flow cytometry, gating on neutrophils by forward/side scatter and/or CD45/side scatter. (B) a healthy control, (C) Abnormal DHR expression in CGD patient, (D) X-linked carrier mother-mosaic pattern. NADPH oxidase component expression (7D5 for anti-gp91phox/p22phox, anti-p47phox, and anti-p67phox) was analyzed on neutrophils cells. (E) a healthy control, (F) Abnormal expression of gp91phox (CYBB gene) or p22phox (CYBA gene) in CGD patient, (G) X-linked carrier mother-mosaic pattern. (H) a healthy control, (I) Abnormal expression of p47phox (NCF1 gene) in CGD patient, (J) a healthy control, (K) Abnormal expression of p67phox (NCF2 gene) in CGD patient.