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Comparison 1: Laronidase versus placebo, Outcome 1: Change in urinary GAG excretion
| Change in urinary GAG excretion | |||
| Study | Urinary GAG excretion in laronidase group (n = 21) | Urinary GAG excretion in placebo group (n = 22) | P‐value |
| Wraith 2004 | Mean reduction of 54.1% | Mean increase of 47.3% | <0.001 |
