Table 1.
A comparison of surgical outcomes for ET
DBS | FUS | GKRS | RF | |
Experience | 1093 patients since 1998 | 151 patients since 2013 | 360 patients since 2007 | 278 patients since 1986 |
Level of Evidence, (OCEM) | Level 2 | Level 1 | Level 4 | Levels 2–4 |
Tremor control, 12-month follow-up | Unilateral: 53.4%–62.8% Bilateral 66%–78% |
Unilateral: 35%–75% Bilateral: no data |
Unilateral: 48%–63% Bilateral: no data |
Unilateral: 74%–90% Bilateral: no data |
Tremor control, long-term follow-up | Unilateral: 60%–75% Bilateral 75% |
Unilateral: 56% |
Unilateral: 3%–63% |
Unilateral: 74%–90% |
Quality of life improvements | 57.9%–82% | 37%–73% | 65% | 47% |
Complications (range, transient and permanent) |
Unilateral, bilateral | |||
Dysarthria | 11%–39%, 22%–75% | 3% | 1%–3% | 4.6%–29% |
Ataxia/gait | 9%–17%, 56%–86% | 23% | 0%–17% | 5%–27% |
Paraesthesia | 5%, 5.9% | 14%–25% | 1%–9% | 6%–42% |
Hemiparesis | 4.5%, 6.7% | 2%–7% | 0%–8% | 0%–34% |
ET, essential tremor; DBS, deep brain stimulation; FUS, focused ultrasound; GKRS, gamma knife radiosurgical thalamotomy; RF, radiofrequency.