Table 4.
Linear Regression Analyses Between Neutrophil Count and Symptomatology, Estimated With the PANSS Scores
| Score | Neutrophil Count | Cannabis Smoking | Years of Education | Antipsych. Medication | BMI | R 2 | F test | P Value |
|---|---|---|---|---|---|---|---|---|
| Total PANSS | 0.173* | 0.245*** | −0.187** | — | — | .136 | 6.966 | <.001 |
| Positive PANSS subscale | 0.166* | — | −0.218*** | −0.250*** | −0.200** | .160 | 6.281 | <.001 |
| P1. Delusions | ns | — | −0.198** | −0.316**** | −0.169* | .167 | 6.608 | <.001 |
| P2. Conceptual disorganization | 0.163 † | — | −0.174* | −0.212** | −0.207** | .132 | 5.008 | <.001 |
| P3. Hallucinatory behavior | 0.182* | — | −0.292**** | ns | −0.238*** | .168 | 6.642 | <.001 |
| P4. Excitement | ns | — | ns | −0.213** | ns | .068 | 2.405 | .053 |
| P5. Grandiosity | ns | — | ns | ns | ns | — | — | — |
| P6. Suspiciousness/persecution | 0.216*** | — | −0.240*** | −0.223*** | ns | .143 | 5.491 | <.001 |
| P7. Hostility | 0.247*** | — | ns | ns | ns | .062 | 2.191 | .073 |
| Negative PANSS subscale | — | — | −0.264*** | — | — | .070 | 10.142 | .002 |
| General PANSS subscale | 0.152 + | 0.296**** | — | — | — | .111 | 8.404 | <.001 |
| G1. Somatic concern | ns | ns | — | — | — | — | — | — |
| G2. Anxiety | ns | 0.182* | — | — | — | .043 | 2.978 | .054 |
| G3. Guilt feelings | ns | ns | — | — | — | — | — | — |
| G4. Tension | ns | 0.259*** | — | — | — | .082 | 5.999 | .003 |
| G5. Mannerisms and posturing | 0.160 † | 0.169* | — | — | — | .055 | 3.872 | .023 |
| G6. Depression | ns | ns | — | — | — | — | — | — |
| G7. Motor retardation | ns | 0.218*** | — | — | — | .066 | 4.751 | .010 |
| G8. Uncooperativeness | ns | 0.234*** | — | — | — | .058 | 4.094 | .019 |
| G9. Unusual thought content | ns | 0.220*** | — | — | — | .068 | 4.914 | .009 |
| G10. Disorientation | ns | 0.345**** | — | — | — | .126 | 9.694 | <.001 |
| G11. Poor attention | ns | 0.209** | — | — | — | .056 | 3.980 | .021 |
| G12. Lack of judgment and insight | ns | ns | — | — | — | — | — | — |
| G13. Disturbance of volition | 0.197** | 0.244*** | — | — | — | .099 | 7.382 | <.001 |
| G14. Poor impulse control | ns | 0.288**** | — | — | — | .090 | 6.599 | .002 |
| G15. Preoccupation | 0.283**** | 0.188** | — | — | — | .117 | 8.848 | <.001 |
| G16. Active social avoidance | ns | 0.172* | — | — | — | .035 | 2.452 | .090 |
Note: The analysis of the individual items of the positive PANSS subscale included neutrophil count, years of education, antipsychotic medication, and BMI as predictors. The analysis of the individual items of the general PANSS subscale included neutrophil count and cannabis smoking as predictors. Uncorrected P values are presented. Statistically significant associations are marked in bold. ns, nonsignificant.
+ P = .064; †P < .06; *P < .05; **P < .025; ***P ≤ .01; ****P < .001.