Table 2.
Meta-analysis Between JPN-SCZ GWAS and PGC-SCZ EUR
| Meta-analysis (JPN-SCZ GWAS+PGC- SCZ EUR) | JPN-SCZ GWAS | PGC-SCZ EUR | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SNP | CHR | BP | Closest Gene | A1/A2 | OR | P-value | Case Freq. (A1) | Control Freq. (A1) | OR | P-value | OR | P-value |
| rs62148129 | 2 | 73204203 | SFXN5 | G/A | 0.921 | 2.19E-08 | 0.620 | 0.636 | 0.925 | 3.95E-02 | 0.921 | 1.94E-07 |
| rs1353545* | 3 | 60287845 | FHIT | C/G | 1.07 | 5.82E-09 | 0.706 | 0.683 | 1.10 | 2.16E-02 | 1.06 | 6.76E-08 |
| rs308693 | 3 | 161485407 | OTOL1 | G/A | 1.07 | 1.75E-08 | 0.854 | 0.840 | 1.16 | 1.53E-02 | 1.06 | 1.41E-07 |
| rs28730912** | 3 | 161779956 | TOMM22P6 | T/C | 1.07 | 9.20E-09 | 0.550 | 0.533 | 1.08 | 4.50E-02 | 1.07 | 6.99E-08 |
| rs314272* | 6 | 105462004 | LIN28B | A/G | 0.944 | 4.18E-08 | 0.706 | 0.721 | 0.922 | 4.18E-02 | 0.946 | 2.93E-07 |
| rs9398171** | 6 | 108983527 | FOXO3 | T/C | 0.938 | 2.13E-08 | 0.734 | 0.754 | 0.907 | 1.91E-02 | 0.941 | 2.53E-07 |
| rs9695226* | 9 | 22759396 | FLJ35282 | A/G | 0.941 | 4.46E-08 | 0.691 | 0.692 | 0.958 | 2.75E-01 | 0.939 | 7.30E-08 |
Note: JPN, Japanese population; SCZ, schizophrenia; GWAS, Genome-Wide Association Study; PGC, Psychiatric GWAS Consortium; EUR, European population; SNP, single nucleotide polymorphism; CHR, chromosome; BP, base position (hg19); A1, effect allele; A2, non-effect allele; Freq, frequency. Bold values indicate 5 × 10−8.
*listed in Goes et al but P > 5E-8, **listed in Goes et al and P < 5E-8.