Table 1.
Total number of newly enrolled patients with amyotrophic lateral sclerosis (ALS) and incidence rates per 100 000 inhabitants in Korea (2011–2015)
| Parameters at first diagnosis | Total number (%) of new patients with ALS* | Use of riluzole % | Tracheostomy % | Incidence (per 105)† |
95% CI |
| Age | |||||
| <40 | 140 (4.6) | 35.7 | 10.7 | 0.11 | 0.07 to 0.15 |
| 40–49 | 335 (11.0) | 60.9 | 16.4 | 0.76 | 0.58 to 0.94 |
| 50–59 | 782 (25.6) | 58.2 | 20.6 | 2.04 | 1.72 to 2.35 |
| ≥60 | 1792 (58.8) | 51.6 | 21.7 | 4.29 | 3.85 to 4.74 |
| Sex | |||||
| Male | 1878 (61.6) | 51.8 | 21.5 | 1.47 | 1.32 to 1.62 |
| Female | 1171 (38.4) | 56.4 | 18.4 | 0.92 | 0.80 to 1.04 |
| Income‡ | |||||
| High | 1088 (35.7) | 53.3 | 22.3 | 1.30 | 1.13 to 1.48 |
| Middle | 1174 (38.5) | 56.0 | 20.4 | 1.01 | 0.88 to 1.14 |
| Low | 787 (25.8) | 50.3 | 17.3 | 1.41 | 1.19 to 1.63 |
| Region | |||||
| Seoul city§ | 601 (19.7) | 55.9 | 21.8 | 1.19 | 0.97 to 1.40 |
| Metropolitan¶ | 707 (23.2) | 54.5 | 21.8 | 1.09 | 0.91 to 1.27 |
| Other areas** | 1741 (57.1) | 52.4 | 19.2 | 1.25 | 1.11 to 1.38 |
| Total | 3049 (100.0) | 53.6 | 20.3 | 1.20 | 1.10 to 1.29 |
| adjusted incidence†† | 0.88 | 0.81 to 0.95 | |||
| Age at diagnosis (mean±SD) | 61.4±12.4 | ||||
| Male:female ratio | 1.60 | ||||
*5 years (2011–2015) total number of new patients.
†Crude incidence rate per 100 000 inhabitants.
‡Income-based insurance contributions.
§Seoul metropolitan city.
¶Other metropolitan cities.
**Non-metropolitan area.
††Age-adjusted incidence (per 100 000 inhabitants) using WHO (2000–2025) world standard population.