Table 5.

Mean survival time from first diagnosis to death (or to the end of follow-up time) or to tracheostomy or death (or to the end of follow-up time)

	Total (N=3049)*						Subgroup (N=714)†
	Death			Tracheostomy or death‡			Death			Tracheostomy or death
	Mean§	SE	P values¶	Mean§	SE	P values¶	Mean§	SE	P values¶	Mean§	SE	P values¶
Age
<40	57.7	1.52	<0.0001	53.4	1.87	<0.0001	57.4	2.57	<0.0001	65.4	3.06	<0.0001
40–49	50.8	1.19		46.4	1.36		50.0	2.14		54.5	2.52
50–59	40.9	0.86		35.3	0.91		37.9	1.69		40.9	1.95
≥60	31.4	0.64		27.0	0.64		30.8	1.29		31.5	1.35
Sex
Male	36.9	0.60	0.9446	31.9	0.62	0.6788	37.0	1.17	0.4278	39.7	1.33	0.4384
Female	38.3	0.82		33.7	0.84		37.4	1.62		38.5	1.72
Income**
High	36.1	0.79	0.6515	31.0	0.81	0.1211	37.4	1.55	0.4472	40.4	1.77	0.5236
Middle	37.5	0.77		32.6	0.80		35.6	1.52		37.6	1.68
Low	39.0	1.00		35.2	1.04		38.8	1.94		40.0	2.06
Region
Seoul city††	38.8	1.05	0.0915	32.9	1.09	0.6661	41.7	1.99	0.0887	44.2	2.23	0.5823
Metropolitan city‡‡	37.8	1.03		30.1	0.92		34.8	2.01		36.4	2.17
Other areas§§	37.6	0.67		33.5	0.69		37.4	1.31		38.6	1.39
Total	38.3	0.51		33.5	0.52		38.0	0.99		39.2	1.05

All lengths of time are in months.

*Total study subjects (N=3049).

†Follow-up more than 5 years from first diagnosis among study subjects (N=714).

‡In total study subjects, there were 25 patients who had an invalid tracheostomy date (underwent tracheostomy before amyotrophic lateral sclerosis diagnosis). When calculating functional end-point survival time in total patients group, we excluded those 25 patients (N=3024).

§Mean survival time from first diagnosis to death or to functional end-point (or to the end of follow-up time).

¶P value by log-rank test.

**Income-based insurance contributions.

††Seoul metropolitan city.

‡‡Other metropolitan cities.

§§Non-metropolitan area.