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. Author manuscript; available in PMC: 2019 Jun 18.
Published in final edited form as: Metabolism. 2016 Sep 22;66:14–22. doi: 10.1016/j.metabol.2016.09.005

Figure 2. The cardiac diastolic dysfunction of western diet feeding was prevented by daily volitional exercise.

Figure 2

A) Representative cine-MRI images of the hearts of a WD fed mouse (WD, upper row of images) and a WD fed mouse treated with exercise (WD+Ex, lower row of images). B) The diastolic relaxation time of the left ventricle (LV) was significantly improved in WD fed mice treated with daily volitional exercise (WD+Ex) compared to sedentary WD fed mice (WD). C) Initial LV filling rate was significantly increased with daily volitional exercise in WD fed mice. D) There was no significant improvement in LV peak filling rate with exercise treatment of WD fed mice. (Dashed line in each graph represents the average value of non-exercised control diet fed mice. N = 6 for WD group and N = 7 for WD+Ex group. * denotes p < 0.05 for WD vs WD+Ex.)