TABLE 3.
Comparison of Lesion and Normal-Organ Uptake and Retention for 68Ga-DOTATATE and 64Cu-SARTATE
| Measure | 68Ga-DOTATATE | 64Cu-SARTATE | Difference | 95% CI | P* |
| Median at 1 h | |||||
| Max lesion SUVmax | 31.65 | 41.90 | 12.45 | 5.1, 21.4 | 0.010 |
| Mean patient SUVmax | 23.61 | 33.32 | 10.35 | 5.4, 15.3 | 0.002 |
| Liver SUVmean | 7.10 | 7.45 | 0.30 | −0.2, 0.8 | 0.24 |
| Spleen SUVmean | 20.40 | 28.25 | 9.05 | 4.0, 14.9 | 0.004 |
| Kidney SUVmean | 13.10 | 20.98 | 6.80 | 5.4, 12.1 | 0.002 |
| Median at 1 h (68Ga-DOTATATE) or 4 h (64Cu-SARTATE) | |||||
| Max lesion SUVmax | 31.65 | 50.50 | 17.10 | 9.6, 36.3 | 0.004 |
| Mean patient SUVmax | 23.61 | 34.80 | 12.99 | 6.3, 27.9 | 0.004 |
| Liver SUVmean | 7.10 | 5.90 | −1.05 | −2.2, 1.0 | 0.19 |
| Spleen SUVmean | 20.40 | 35.55 | 17.50 | 7.7, 102.2 | 0.020 |
| Kidney SUVmean | 13.10 | 18.05 | 4.86 | 2.1, 7.0 | 0.004 |
*
Paired Wilcoxon test on 10 patients.
CI = confidence interval; max lesion = most intense lesion; mean patient = mean of up to 5 reference lesions.