Table 1. Discriminatory m/z Values That Are Significantly Elevated (AUC > 0.8) in Ischemically Damaged Renal Tissuea.
| MALDI-ToF m/z | AUC | orbitrap m/z | lipid-sum composition | PPM m/z error |
|---|---|---|---|---|
| Negative-Ion Mode | ||||
| 619.3 | 0.85 | 619.28815 | [LPI(20:4)–H]− | –1.2 |
| 1185.8 | 0.89 | 1185.73349 | [MLCL(54:6)–H]− | –1.5 |
| 1207.8 | 0.85 | 1207.71537 | [MLCL(54:6)–2H+Na]− | –1.5 |
| Positive-Ion Mode | ||||
| 480.8 | 0.87 | 480.34436 | [LPC(O-16:1)+H]+ | –1.0 |
| 496.4 | 0.81 | 496.33935 | [LPC(16:0)+H]+ | –0.8 |
| 520.4 | 0.84 | 520.33924 | [LPC(18:2)+H]+ | –1.0 |
| 522.4 | 0.82 | 522.35495 | [LPC(18:1)+H]+ | –0.9 |
| 524.4 | 0.82 | 524.37059 | [LPC(18:0)+H]+ | –0.9 |
| 544.4 | 0.80 | 544.33805 | [LPC(18:1)+Na]+ | 1.3 |
| 546.4 | 0.82 | 546.35264 | [LPC(18:0)+Na]+ | –0.7 |
a
Only monoisotopic lipids are shown. Lipids were identified following ROC analysis of tissues exposed to cold and warm ischemia. No discriminative ions elevated in the cold-ischemic tissue were observed.