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. 2018 Nov 14;35(12):2100–2107. doi: 10.1093/bioinformatics/bty906

Table 4.

Predicted drug–target interactions with evidence support

Drug name Target Target rank Reference
Pregabalin Dopamine Receptor D2 Top 0.56% PMID22489711
Oxycodone Proenkephalin Top 0.54% PMID30059705
Citalopram Solute Carrier Family 6 Member 2 Top 0.22% J. Med. Chem., 2003, 46 (6), pp 925-935
Bupropion Opioid Receptor Mu 1 Top 0.26% PMID25436082
Naltrexone 5-Hydroxytryptamine Receptor 2A Top 0.45% PMID24395673